Aṣa was born in Paris to Nigerian parents who were working and studying cinematography in France. Her family returned to live in Nigeria when she was two. Aṣa grew up in Lagos city, in the south-western part of Nigeria, and 18 years later, returned to Paris, where her life as an artist took off.
Asa's music influences grew over the years from the collection of great music her father had built up for his work as a cinematographer. These records featuring American, Nigerian and African soul classics, included musical greats such as Marvin Gaye, Fela Kuti, Bob Marley, Aretha Franklin, King Sunny Adé, Diana Ross, Nina Simone, Miriam Makeba. Aṣa went on to draw inspiration from them.
In 2004, Asa met her manager and friend, Janet Nwose, who introduced her to Cobhams Emmanuel Asuquo, who in turn became the producer of her first studio album Asa (Asha).
Her second album, Beautiful Imperfection, in collaboration with French composer Nicolas Mollard, was released on 25 October 2010, went platinum in 2011. The lead single from Beautiful Imperfection is titled "Be My Man" was released in late September 2010. It was reported that by 2014 Aṣa sold 400,000 albums worldwide.
Asa's third studio album, Bed of Stone, was released in August 2014. The singles are "Dead Again", "Eyo", "Satan Be Gone", "The One That Never Comes" and "Moving On". She went on a world tour from 2015 to 2017.
On 14 May 2019, she released a new single titled "The Beginning" and on 25 June 2019 she released the single "Good Thing". On 11 September 2019, she announced on her Twitter page that her new album, Lucid, will be released on 11 October 2019. True to her words, the album was then released on 11 October 2019.